Fibroblast Growth Factors (FGFs) play a crucial role in cellular growth, development, and healing processes. This class of growth factors consists of twenty-three members, each contributing to various biological functions that include embryonic development, cell growth, morphogenesis, tissue repair, and even tumor growth and invasion. The disruption of the signaling pathways associated with FGFs has been linked to numerous health issues, such as cancer, diabetes, and cardiovascular diseases. Consequently, targeting FGFs and their receptors presents a potential avenue for therapeutic interventions.
Key Characteristics and Applications
Fibroblast Growth Factors (FGFs) possesses unique properties that make it indispensable in biomedical research and therapeutic applications. Notably, FGFs have a long biological half-life and the ability to stimulate tissue proliferation and differentiation. This capability allows FGFs to promote effective tissue growth and repair, making them a vital component in various research applications.
Areas of Application
- Cell Culture: FGFs are integral in promoting cell proliferation and differentiation, thus enhancing cell culture techniques that support cellular growth and division.
- Hematopoietic Cell Regulation: These growth factors exert a regulatory influence on the proliferation and differentiation of hematopoietic stem cells, which facilitates the expansion of these cells in vitro and enhances hematopoietic efficiency.
- Tissue Regeneration: FGFs foster cellular proliferation and tissue repair, playing a significant role in skin and vascular tissue recovery.
- Neuroscience: FGFs contribute significantly to neuronal development and regeneration, providing essential insights into neurological research.
- Oncology: With some tumors displaying overexpression of FGF receptors, FGFs can inhibit tumor growth by competitively binding to these receptors, making them vital in cancer research.
- Anti-Aging Studies: By promoting cellular proliferation and differentiation, FGFs can help delay the aging process.
Product Offerings at Creative Bioarray
Creative Bioarray offers a range of FGFs that are rigorously tested to ensure quality and effectiveness. Among the notable products are:
- GMP Human FGF1
- GMP Human FGF2
- GMP Human FGF7, Fc Tag
- GMP Human FGF8, Fc Tag
- Human FGF10 (Animal Component-Free)
Each product is produced with varying sources such as E. coli, CHO, and HEK293, allowing for versatility in research and application.
Conclusion
Fibroblast Growth Factors represent a pivotal area of study within cell biology, with wide-ranging applications in research and therapeutic endeavors. With ongoing research and development, the potential of FGFs in medicine continues to expand, paving the way for innovative treatments and interventions for various health conditions.
